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Activated fibronectin-secretory phenotype of mesenchymal stromal cells in pre-fibrotic myeloproliferative neoplasms

We characterized bone marrow stromal cells (BMSC) from patients with pre-fibrotic myeloproliferative neoplasms (MPN). MPN-BMSC showed decreased capacity to stimulate the proliferation of colony-forming units of normal hematopoietic stem and progenitor cells and displayed increased matrix remodelling...

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Detalles Bibliográficos
Autores principales: Schneider, Rebekka K, Ziegler, Susanne, Leisten, Isabelle, Ferreira, Monica SV, Schumacher, Anne, Rath, Björn, Fahrenkamp, Dirk, Müller-Newen, Gerhard, Crysandt, Martina, Wilop, Stefan, Jost, Edgar, Koschmieder, Steffen, Knüchel, Ruth, Brümmendorf, Tim H, Ziegler, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271470/
https://www.ncbi.nlm.nih.gov/pubmed/25498831
http://dx.doi.org/10.1186/s13045-014-0092-2