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IGFBP-4 and −5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells

BACKGROUND: Adverse gestational outcomes such as preeclampsia (PE) and intrauterine growth restriction (IUGR) are associated with placental insufficiency. Normal placental development relies on the insulin-like growth factors -I and -II (IGF-I and -II), in part to stimulate trophoblast proliferation...

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Detalles Bibliográficos
Autores principales: Crosley, Erin J, Dunk, Caroline E, Beristain, Alexander G, Christians, Julian K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271501/
https://www.ncbi.nlm.nih.gov/pubmed/25475528
http://dx.doi.org/10.1186/1477-7827-12-123