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Leptin Receptor Mutation Results in Defective Neutrophil Recruitment to the Colon during Entamoeba histolytica Infection

Amebiasis is an enteric infection caused by Entamoeba histolytica, with symptoms ranging in severity from asymptomatic colonization to dysentery. Humans with the Q223R leptin receptor mutation have increased susceptibility to amebiasis, but the mechanism has been unclear. Using a mouse model express...

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Detalles Bibliográficos
Autores principales: Naylor, Caitlin, Burgess, Stacey, Madan, Rajat, Buonomo, Erica, Razzaq, Khadija, Ralston, Katherine, Petri, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271549/
https://www.ncbi.nlm.nih.gov/pubmed/25516614
http://dx.doi.org/10.1128/mBio.02046-14