Sirtuins Are Evolutionarily Conserved Viral Restriction Factors

The seven human sirtuins are a family of ubiquitously expressed and evolutionarily conserved NAD(+)-dependent deacylases/mono-ADP ribosyltransferases that regulate numerous cellular and organismal functions, including metabolism, cell cycle, and longevity. Here, we report the discovery that all seve...

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Detalles Bibliográficos
Autores principales: Koyuncu, Emre, Budayeva, Hanna G., Miteva, Yana V., Ricci, Dante P., Silhavy, Thomas J., Shenk, Thomas, Cristea, Ileana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271551/
https://www.ncbi.nlm.nih.gov/pubmed/25516616
http://dx.doi.org/10.1128/mBio.02249-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271551/
https://www.ncbi.nlm.nih.gov/pubmed/25516616
http://dx.doi.org/10.1128/mBio.02249-14

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