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Dynamics of Lewis b Binding and Sequence Variation of the babA Adhesin Gene during Chronic Helicobacter pylori Infection in Humans

Helicobacter pylori undergoes rapid microevolution during chronic infection, but very little is known about how this affects host interaction factors. The best-studied adhesin of H. pylori is BabA, which mediates binding to the blood group antigen Lewis b [Le(b)]. To study the dynamics of Le(b) adhe...

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Detalles Bibliográficos
Autores principales: Nell, Sandra, Kennemann, Lynn, Schwarz, Sandra, Josenhans, Christine, Suerbaum, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271554/
https://www.ncbi.nlm.nih.gov/pubmed/25516619
http://dx.doi.org/10.1128/mBio.02281-14