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Reverse engineering gene regulatory networks: Coupling an optimization algorithm with a parameter identification technique

BACKGROUND: To infer gene regulatory networks from time series gene profiles, two important tasks that are related to biological systems must be undertaken. One task is to determine a valid network structure that has topological properties that can influence the network dynamics profoundly. The othe...

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Detalles Bibliográficos
Autores principales: Hsiao, Yu-Ting, Lee, Wei-Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271569/
https://www.ncbi.nlm.nih.gov/pubmed/25474560
http://dx.doi.org/10.1186/1471-2105-15-S15-S8