Fanconi Anemia Repair Pathway Dysfunction, a Potential Therapeutic Target in Lung Cancer

The Fanconi anemia (FA) pathway is a major mechanism of homologous recombination DNA repair. The functional readout of the pathway is activation through mono-ubiquitination of FANCD2 leading to nuclear foci of repair. We have recently developed an FA triple-staining immunofluorescence based method (...

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Detalles Bibliográficos
Autores principales: Duan, Wenrui, Gao, Li, Aguila, Brittany, Kalvala, Arjun, Otterson, Gregory A., Villalona-Calero, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271581/
https://www.ncbi.nlm.nih.gov/pubmed/25566506
http://dx.doi.org/10.3389/fonc.2014.00368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271581/
https://www.ncbi.nlm.nih.gov/pubmed/25566506
http://dx.doi.org/10.3389/fonc.2014.00368

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