Maintenance of Leukemia-Initiating Cells Is Regulated by the CDK Inhibitor Inca1

Functional differences between healthy progenitor and cancer initiating cells may provide unique opportunities for targeted therapy approaches. Hematopoietic stem cells are tightly controlled by a network of CDK inhibitors that govern proliferation and prevent stem cell exhaustion. Loss of Inca1 led...

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Detalles Bibliográficos
Autores principales: Bäumer, Nicole, Bäumer, Sebastian, Berkenfeld, Frank, Stehling, Martin, Köhler, Gabriele, Berdel, Wolfgang E., Müller-Tidow, Carsten, Tschanter, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272264/
https://www.ncbi.nlm.nih.gov/pubmed/25525809
http://dx.doi.org/10.1371/journal.pone.0115578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272264/
https://www.ncbi.nlm.nih.gov/pubmed/25525809
http://dx.doi.org/10.1371/journal.pone.0115578

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