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The Synergistic Repressive Effect of NF-κB and JNK Inhibitor on the Clonogenic Capacity of Jurkat Leukemia Cells

Deregulation of Nuclear Transcription Factor-κB (NF-κB) and Jun N-terminal kinase (JNK) signaling is commonly detected in leukemia, suggesting an important role for these two signaling pathways in the pathogenesis of leukemia. In this study, using Jurkat cells, an acute T-lymphoblastic leukemia (T-A...

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Detalles Bibliográficos
Autores principales: Liu, Xinli, Zhang, Jun, Li, Jing, Volk, Andrew, Breslin, Peter, Zhang, Jiwang, Zhang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272284/
https://www.ncbi.nlm.nih.gov/pubmed/25526629
http://dx.doi.org/10.1371/journal.pone.0115490