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Effect of ecto-5′-nucleotidase (eN) in astrocytes on adenosine and inosine formation
ATP is a gliotransmitter released from astrocytes. Extracellularly, ATP is metabolized by a series of enzymes, including ecto-5′-nucleotidase (eN; also known as CD73) which is encoded by the gene 5NTE and functions to form adenosine (ADO) from adenosine monophosphate (AMP). Under ischemic conditions...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272361/ https://www.ncbi.nlm.nih.gov/pubmed/25129451 http://dx.doi.org/10.1007/s11302-014-9421-8 |