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Identification and Characterization of an eIF4e DNA Aptamer That Inhibits Proliferation With High Throughput Sequencing

Development of DNA aptamer screens that are both simple and informative can increase the success rate of DNA aptamer selection and induce greater adoption. High eIF4e levels contribute to malignancies, thus eIF4e presents itself as a valuable target for DNA aptamer-based inhibition screen. Here, we...

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Detalles Bibliográficos
Autores principales: Guo, Wei Mei, Kong, Kiat Whye, Brown, Christopher John, Quah, Soo Tng, Yeo, Hui Ling, Hoon, Shawn, Seow, Yiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272410/
https://www.ncbi.nlm.nih.gov/pubmed/25514650
http://dx.doi.org/10.1038/mtna.2014.70