Systematic identification and quantification of phase variation in commensal and pathogenic Escherichia coli

Bacteria have been shown to generate constant genetic variation in a process termed phase variation. We present a tool based on whole genome sequencing that allows detection and quantification of coexisting genotypes mediated by genomic inversions in bacterial cultures. We tested our method on widel...

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Detalles Bibliográficos
Autores principales: Goldberg, Amir, Fridman, Ofer, Ronin, Irine, Balaban, Nathalie Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272514/
https://www.ncbi.nlm.nih.gov/pubmed/25530806
http://dx.doi.org/10.1186/s13073-014-0112-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272514/
https://www.ncbi.nlm.nih.gov/pubmed/25530806
http://dx.doi.org/10.1186/s13073-014-0112-4

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