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Systematic identification and quantification of phase variation in commensal and pathogenic Escherichia coli
Bacteria have been shown to generate constant genetic variation in a process termed phase variation. We present a tool based on whole genome sequencing that allows detection and quantification of coexisting genotypes mediated by genomic inversions in bacterial cultures. We tested our method on widel...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272514/ https://www.ncbi.nlm.nih.gov/pubmed/25530806 http://dx.doi.org/10.1186/s13073-014-0112-4 |