Estrogen receptor alpha deficiency protects against development of cognitive impairment in murine lupus

BACKGROUND: One of the more profound features of systemic lupus erythematosus (SLE) is that females have a 9:1 prevalence of this disease over males. Up to 80% of SLE patients have cognitive defects or affective disorders. The mechanism of CNS injury responsible for cognitive impairment is unknown....

Descripción completa

Detalles Bibliográficos
Autores principales: Cunningham, Melissa A, Wirth, Jena R, Freeman, Linnea R, Boger, Heather A, Granholm, Ann-Charlotte, Gilkeson, Gary S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272530/
https://www.ncbi.nlm.nih.gov/pubmed/25510908
http://dx.doi.org/10.1186/s12974-014-0171-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272530/
https://www.ncbi.nlm.nih.gov/pubmed/25510908
http://dx.doi.org/10.1186/s12974-014-0171-x

Ejemplares similares