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A genomic and evolutionary approach reveals non-genetic drug resistance in malaria
BACKGROUND: Drug resistance remains a major public health challenge for malaria treatment and eradication. Individual loci associated with drug resistance to many antimalarials have been identified, but their epistasis with other resistance mechanisms has not yet been elucidated. RESULTS: We previou...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272547/ https://www.ncbi.nlm.nih.gov/pubmed/25395010 http://dx.doi.org/10.1186/s13059-014-0511-2 |