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A genomic and evolutionary approach reveals non-genetic drug resistance in malaria

BACKGROUND: Drug resistance remains a major public health challenge for malaria treatment and eradication. Individual loci associated with drug resistance to many antimalarials have been identified, but their epistasis with other resistance mechanisms has not yet been elucidated. RESULTS: We previou...

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Detalles Bibliográficos
Autores principales: Herman, Jonathan D, Rice, Daniel P, Ribacke, Ulf, Silterra, Jacob, Deik, Amy A, Moss, Eli L, Broadbent, Kate M, Neafsey, Daniel E, Desai, Michael M, Clish, Clary B, Mazitschek, Ralph, Wirth, Dyann F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272547/
https://www.ncbi.nlm.nih.gov/pubmed/25395010
http://dx.doi.org/10.1186/s13059-014-0511-2