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The differential susceptibilities of MCF-7 and MDA-MB-231 cells to the cytotoxic effects of curcumin are associated with the PI3K/Akt-SKP2-Cip/Kips pathway

BACKGROUND: The mechanism underlying the differential cytotoxicity of curcumin in various cancer types, however, remains largely unclear. The aims of this study is to examine the concentration- and time-related effects of curcumin on two different breast cancer cells, MCF-7 and MDA-MB-231, and inves...

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Detalles Bibliográficos
Autores principales: Jia, Tao, Zhang, Li, Duan, Yale, Zhang, Min, Wang, Gang, Zhang, Jun, Zhao, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272549/
https://www.ncbi.nlm.nih.gov/pubmed/25530715
http://dx.doi.org/10.1186/s12935-014-0126-4