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Effects of antibody to receptor activator of nuclear factor κ-B ligand on inflammation and cartilage degradation in collagen antibody-induced arthritis in mice

BACKGROUND: Rheumatoid arthritis (RA) is an inflammatory disease that leads to destruction of both articular cartilage and bone tissues. In rheumatic joints, synoviocytes and T-lymphocytes as well as bone cells produce the receptor activator of nuclear factor κ-B (RANK) ligand (RANKL), which binds t...

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Detalles Bibliográficos
Autores principales: Funato, Sakie, Matsunaga, Akihiro, Oh, Koei, Miyamoto, Yoichi, Yoshimura, Kentaro, Tanaka, Junichi, Suzuki, Dai, Uyama, Risa, Suzuki, Hiroaki, Mishima, Kenji, Nakamura, Masanori, Namiki, Osamu, Baba, Kazuyoshi, Inagaki, Katsunori, Kamijo, Ryutaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272563/
https://www.ncbi.nlm.nih.gov/pubmed/25495344
http://dx.doi.org/10.1186/s12952-014-0018-0