High throughput exome coverage of clinically relevant cardiac genes

BACKGROUND: Given the growing use of whole-exome sequencing (WES) for clinical diagnostics of complex human disorders, we evaluated coverage of clinically relevant cardiac genes on WES and factors influencing uniformity and depth of coverage of exonic regions. METHODS: Two hundred and thirteen human...

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Detalles Bibliográficos
Autores principales: Manase, Dorin, D’Alessandro, Lisa CA, Manickaraj, Ashok Kumar, Al Turki, Saeed, Hurles, Matthew E, Mital, Seema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272796/
https://www.ncbi.nlm.nih.gov/pubmed/25496018
http://dx.doi.org/10.1186/s12920-014-0067-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272796/
https://www.ncbi.nlm.nih.gov/pubmed/25496018
http://dx.doi.org/10.1186/s12920-014-0067-8

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