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Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers

Mitochondria are important intracellular organelles that produce energy for cellular development, differentiation, and growth. Mitochondrial DNA (mtDNA) presents a 10- to 20-fold higher susceptibility to genetic mutations owing to the lack of introns and histone proteins. The mtDNA repair system is...

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Detalles Bibliográficos
Autores principales: Kim, Hye-Ran, Won, Stephanie Jane, Fabian, Claire, Kang, Min-Gu, Szardenings, Michael, Shin, Myung-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272938/
https://www.ncbi.nlm.nih.gov/pubmed/25553274
http://dx.doi.org/10.3343/alm.2015.35.1.1