Cargando…
Mitochondrial DNA Aberrations and Pathophysiological Implications in Hematopoietic Diseases, Chronic Inflammatory Diseases, and Cancers
Mitochondria are important intracellular organelles that produce energy for cellular development, differentiation, and growth. Mitochondrial DNA (mtDNA) presents a 10- to 20-fold higher susceptibility to genetic mutations owing to the lack of introns and histone proteins. The mtDNA repair system is...
Autores principales: | Kim, Hye-Ran, Won, Stephanie Jane, Fabian, Claire, Kang, Min-Gu, Szardenings, Michael, Shin, Myung-Geun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Laboratory Medicine
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272938/ https://www.ncbi.nlm.nih.gov/pubmed/25553274 http://dx.doi.org/10.3343/alm.2015.35.1.1 |
Ejemplares similares
-
Clinicopathological Implications of Mitochondrial Genome Alterations in Pediatric Acute Myeloid Leukemia
por: Kang, Min-Gu, et al.
Publicado: (2016) -
Rejuvenating Aged Hematopoietic Stem Cells Through Improvement of Mitochondrial Function
por: Moon, James, et al.
Publicado: (2018) -
Mitochondrial DNA Aberrations of Bone Marrow Cells from Patients with Aplastic Anemia
por: Kim, Hye-Ran, et al.
Publicado: (2008) -
Coexistence of JAK2 and CALR mutations and their clinical implications in patients with essential thrombocythemia
por: Kang, Min-Gu, et al.
Publicado: (2016) -
Direct confirmation of quiescence of CD34+CD38- leukemia stem cell populations using single cell culture, their molecular signature and clinicopathological implications
por: Won, Eun Jeong, et al.
Publicado: (2015)