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Alteration of the SETBP1 Gene and Splicing Pathway Genes SF3B1, U2AF1, and SRSF2 in Childhood Acute Myeloid Leukemia

BACKGROUND: Recurrent somatic SET-binding protein 1 (SETBP1) and splicing pathway gene mutations have recently been found in atypical chronic myeloid leukemia and other hematologic malignancies. These mutations have been comprehensively analyzed in adult AML, but not in childhood AML. We investigate...

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Detalles Bibliográficos
Autores principales: Choi, Hyun-Woo, Kim, Hye-Ran, Baek, Hee-Jo, Kook, Hoon, Cho, Duck, Shin, Jong-Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Shin, Myung-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272941/
https://www.ncbi.nlm.nih.gov/pubmed/25553291
http://dx.doi.org/10.3343/alm.2015.35.1.118