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Regulation of the Target Protein (Transgene) Expression in the Adenovirus Vector Using Agonists of Toll-Like Receptors

Replication-defective adenoviral vectors are effective molecular tools for both gene therapy and gene vaccination. Using such vectors one can deliver and express target genes in different epithelial, liver, hematopoietic and immune system cells of animal and human origin. The success of gene therapy...

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Detalles Bibliográficos
Autores principales: Bagaev, A. V., Pichugin, A. V., Lebedeva, E. S., Lysenko, A. A., Shmarov, M. M., Logunov, D. Yu., Naroditsky, B. S., Ataullakhanov, R. I., Khaitov, R. M., Gintsburg, A. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273089/
https://www.ncbi.nlm.nih.gov/pubmed/25558392