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STIM1 Protein Activates Store-Operated Calcium Channels in Cellular Model of Huntington’s Disease

We have shown that the expression of full-length mutated huntingtin in human neuroblastoma cells (SK-N-SH) leads to an abnormal increase in calcium entry through store-operated channels. In this paper, the expression of the N-terminal fragment of mutated huntingtin (Htt138Q-1exon) is shown to be eno...

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Detalles Bibliográficos
Autores principales: Vigont, V. A., Zimina, O. A., Glushankova, L. N., Kolobkova, J. A., Ryazantseva, M. A., Mozhayeva, G. N., Kaznacheyeva, E. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273090/
https://www.ncbi.nlm.nih.gov/pubmed/25558393