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Phosphoryl Guanidines: A New Type of Nucleic Acid Analogues

A new type of nucleic acid analogues with a phosphoryl guanidine group is described. Oxidation of polymer-supported dinucleoside 2-cyanoethyl phosphite by iodine in the presence of 1,1,3,3-tetramethyl guanidine yields a dinucleotide with an internucleoside tetramethyl phosphoryl guanidine (Tmg) grou...

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Detalles Bibliográficos
Autores principales: Kupryushkin, M. S., Pyshnyi, D. V., Stetsenko, D. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273099/
https://www.ncbi.nlm.nih.gov/pubmed/25558402