A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes

A novel metal-free strategy for a rapid and α-selctive C-alkynylation of glycals was developed. The reaction utilizes TMSOTf as a promoter to generate in situ trimethylsilylacetylene for C-alkynylation. Thanks to this methodology, we can access C-glycosides in a single step from a variety of acetyle...

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Detalles Bibliográficos
Autores principales: Devari, Shekaraiah, Kumar, Manjeet, Deshidi, Ramesh, Rizvi, Masood, Shah, Bhahwal Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273296/
https://www.ncbi.nlm.nih.gov/pubmed/25550726
http://dx.doi.org/10.3762/bjoc.10.277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273296/
https://www.ncbi.nlm.nih.gov/pubmed/25550726
http://dx.doi.org/10.3762/bjoc.10.277

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