A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

A highly efficacious pre-erythrocytic stage vaccine would be an important tool for the control and elimination of malaria but is currently unavailable. High-level protection in humans can be achieved by experimental immunization with Plasmodium falciparum sporozoites attenuated by radiation or under...

Descripción completa

Detalles Bibliográficos
Autores principales: van Schaijk, Ben C L, Ploemen, Ivo H J, Annoura, Takeshi, Vos, Martijn W, Foquet, Lander, van Gemert, Geert-Jan, Chevalley-Maurel, Severine, van de Vegte-Bolmer, Marga, Sajid, Mohammed, Franetich, Jean-Francois, Lorthiois, Audrey, Leroux-Roels, Geert, Meuleman, Philip, Hermsen, Cornelius C, Mazier, Dominique, Hoffman, Stephen L, Janse, Chris J, Khan, Shahid M, Sauerwein, Robert W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273440/
https://www.ncbi.nlm.nih.gov/pubmed/25407681
http://dx.doi.org/10.7554/eLife.03582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273440/
https://www.ncbi.nlm.nih.gov/pubmed/25407681
http://dx.doi.org/10.7554/eLife.03582

Ejemplares similares