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Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR) significan...

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Detalles Bibliográficos
Autores principales: Hostettler, Katrin E, Zhong, Jun, Papakonstantinou, Eleni, Karakiulakis, George, Tamm, Michael, Seidel, Petra, Sun, Qingzhu, Mandal, Jyotshna, Lardinois, Didier, Lambers, Christopher, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273482/
https://www.ncbi.nlm.nih.gov/pubmed/25496490
http://dx.doi.org/10.1186/s12931-014-0157-3