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Anti-fibrotic effects of nintedanib in lung fibroblasts derived from patients with idiopathic pulmonary fibrosis
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with poor prognosis. The kinase inhibitor nintedanib specific for vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR) significan...
Autores principales: | Hostettler, Katrin E, Zhong, Jun, Papakonstantinou, Eleni, Karakiulakis, George, Tamm, Michael, Seidel, Petra, Sun, Qingzhu, Mandal, Jyotshna, Lardinois, Didier, Lambers, Christopher, Roth, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273482/ https://www.ncbi.nlm.nih.gov/pubmed/25496490 http://dx.doi.org/10.1186/s12931-014-0157-3 |
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