A Predictive HQSAR Model for a Series of Tricycle Core Containing MMP-12 Inhibitors with Dibenzofuran Ring

MMP-12 is a member of matrix metalloproteinases (MMPs) family involved in pathogenesis of some inflammatory based diseases. Design of selective matrix MMPs inhibitors is still challenging because of binding pocket similarities among MMPs family. We tried to generate a HQSAR (hologram quantitative st...

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Detalles Bibliográficos
Autores principales: Shamsara, Jamal, Shahir-Sadr, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273529/
https://www.ncbi.nlm.nih.gov/pubmed/25574392
http://dx.doi.org/10.1155/2014/630807

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273529/
https://www.ncbi.nlm.nih.gov/pubmed/25574392
http://dx.doi.org/10.1155/2014/630807

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