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p53 binding to human genome: crowd control navigation in chromatin context
p53 is the most studied human protein because of its role in maintaining genomic stability. Binding to genomic targets is essential for transcription-dependent p53 tumor suppression, but how p53 selects targets remains unclear. Here, the impact of chromatin context on p53 genome-wide binding and tar...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273661/ https://www.ncbi.nlm.nih.gov/pubmed/25566329 http://dx.doi.org/10.3389/fgene.2014.00447 |