Dual effects of Rho-kinase inhibitors on a rat model of inflammatory pain

BACKGROUND: Rho-kinases (ROCKs), a family of small GTP-dependent enzymes, are involved in a range of pain models, and their inhibition typically leads to antinociceptive effects. OBJECTIVES: To study the effects of inhibiting ROCKs using two known inhibitors, Y27632 and HA1077 (fasudil), administere...

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Detalles Bibliográficos
Autores principales: Paiva-Lima, Patricia, Bakhle, YS, Francischi, Janetti N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pulsus Group Inc 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273717/
https://www.ncbi.nlm.nih.gov/pubmed/24992453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273717/
https://www.ncbi.nlm.nih.gov/pubmed/24992453

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