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Metalloproteinase-Dependent TLR2 Ectodomain Shedding is Involved in Soluble Toll-Like Receptor 2 (sTLR2) Production

Toll-like receptor (TLR) 2, a type I membrane receptor that plays a key role in innate immunity, recognizes conserved molecules in pathogens, and triggering an inflammatory response. It has been associated with inflammatory and autoimmune diseases. Soluble TLR2 (sTLR2) variants have been identified...

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Detalles Bibliográficos
Autores principales: Langjahr, Patricia, Díaz-Jiménez, David, De la Fuente, Marjorie, Rubio, Estefhany, Golenbock, Douglas, Bronfman, Francisca C., Quera, Rodrigo, González, María-Julieta, Hermoso, Marcela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273945/
https://www.ncbi.nlm.nih.gov/pubmed/25531754
http://dx.doi.org/10.1371/journal.pone.0104624