Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model

Methotrexate (MTX) is a pro-oxidant compound that depletes dihydrofolate pools and is widely used in the treatment of leukaemia and other malignancies. The efficacy of methotrexate is often limited by mucositis and intestinal injury, which are major causes of morbidity in children and adults. The ai...

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Detalles Bibliográficos
Autores principales: de Araújo Júnior, Raimundo Fernandes, da Silva Reinaldo, Maria Patrícia Oliveira, Brito, Gerly Anne de Castro, Cavalcanti, Pedro de França, Freire, Marco Aurélio de Moura, de Medeiros, Caroline Addison Xavier, de Araújo, Aurigena Antunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273993/
https://www.ncbi.nlm.nih.gov/pubmed/25531650
http://dx.doi.org/10.1371/journal.pone.0114923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273993/
https://www.ncbi.nlm.nih.gov/pubmed/25531650
http://dx.doi.org/10.1371/journal.pone.0114923

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