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Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations

RATIONALE: TRPM4 is a non-selective Ca(2+)-activated cation channel expressed in the heart, particularly in the atria or conduction tissue. Mutations in the Trpm4 gene were recently associated with several human conduction disorders such as Brugada syndrome. TRPM4 channel has also been implicated at...

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Detalles Bibliográficos
Autores principales: Demion, Marie, Thireau, Jérôme, Gueffier, Mélanie, Finan, Amanda, Khoueiry, Ziad, Cassan, Cécile, Serafini, Nicolas, Aimond, Franck, Granier, Mathieu, Pasquié, Jean-Luc, Launay, Pierre, Richard, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274076/
https://www.ncbi.nlm.nih.gov/pubmed/25531103
http://dx.doi.org/10.1371/journal.pone.0115256