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Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations
RATIONALE: TRPM4 is a non-selective Ca(2+)-activated cation channel expressed in the heart, particularly in the atria or conduction tissue. Mutations in the Trpm4 gene were recently associated with several human conduction disorders such as Brugada syndrome. TRPM4 channel has also been implicated at...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274076/ https://www.ncbi.nlm.nih.gov/pubmed/25531103 http://dx.doi.org/10.1371/journal.pone.0115256 |