Long-Term Quiescent Fibroblast Cells Transit into Senescence

Cellular senescence is described to be a consequence of telomere erosion during the replicative life span of primary human cells. Quiescence should therefore not contribute to cellular aging but rather extend lifespan. Here we tested this hypothesis and demonstrate that cultured long-term quiescent...

Descripción completa

Detalles Bibliográficos
Autores principales: Marthandan, Shiva, Priebe, Steffen, Hemmerich, Peter, Klement, Karolin, Diekmann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274099/
https://www.ncbi.nlm.nih.gov/pubmed/25531649
http://dx.doi.org/10.1371/journal.pone.0115597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274099/
https://www.ncbi.nlm.nih.gov/pubmed/25531649
http://dx.doi.org/10.1371/journal.pone.0115597

Ejemplares similares