MiR-338-3p Inhibits Hepatocarcinoma Cells and Sensitizes These Cells to Sorafenib by Targeting Hypoxia-Induced Factor 1α

Hypoxia is a common feature of solid tumors and an important contributor to anti-tumor drug resistance. Hypoxia inducible factor-1 (HIF-1) is one of the key mediators of the hypoxia signaling pathway, and was recently proven to be required for sorafenib resistance in hepatocarcinoma (HCC). MicroRNAs...

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Detalles Bibliográficos
Autores principales: Xu, Haitao, Zhao, Liang, Fang, Qiuju, Sun, Jianmin, Zhang, Songyan, Zhan, Chao, Liu, Shujie, Zhang, Yubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274118/
https://www.ncbi.nlm.nih.gov/pubmed/25531114
http://dx.doi.org/10.1371/journal.pone.0115565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274118/
https://www.ncbi.nlm.nih.gov/pubmed/25531114
http://dx.doi.org/10.1371/journal.pone.0115565

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