DEAF1 Binds Unmethylated and Variably Spaced CpG Dinucleotide Motifs

DEAF1 is a transcriptional regulator associated with autoimmune and neurological disorders and is known to bind TTCG motifs. To further ascertain preferred DEAF1 DNA ligands, we screened a random oligonucleotide library containing an “anchored” CpG motif. We identified a binding consensus that gener...

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Detalles Bibliográficos
Autores principales: Jensik, Philip J., Vargas, Jesse D., Reardon, Sara N., Rajamanickam, Shivakumar, Huggenvik, Jodi I., Collard, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274154/
https://www.ncbi.nlm.nih.gov/pubmed/25531106
http://dx.doi.org/10.1371/journal.pone.0115908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274154/
https://www.ncbi.nlm.nih.gov/pubmed/25531106
http://dx.doi.org/10.1371/journal.pone.0115908

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