KIF4A and PP2A–B56 form a spatially restricted feedback loop opposing Aurora B at the anaphase central spindle

The mitotic kinase Aurora B is concentrated at the anaphase central spindle by the kinesin MKlp2 during mitotic exit and cytokinesis. This pool of Aurora B phosphorylates substrates including the kinesin KIF4A to regulate central spindle length. In this paper, we identify a counteracting system in w...

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Detalles Bibliográficos
Autores principales: Bastos, Ricardo Nunes, Cundell, Michael J., Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274259/
https://www.ncbi.nlm.nih.gov/pubmed/25512391
http://dx.doi.org/10.1083/jcb.201409129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274259/
https://www.ncbi.nlm.nih.gov/pubmed/25512391
http://dx.doi.org/10.1083/jcb.201409129

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