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A PIK3C3–Ankyrin-B–Dynactin pathway promotes axonal growth and multiorganelle transport

Axon growth requires long-range transport of organelles, but how these cargoes recruit their motors and how their traffic is regulated are not fully resolved. In this paper, we identify a new pathway based on the class III PI3-kinase (PIK3C3), ankyrin-B (AnkB), and dynactin, which promotes fast axon...

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Detalles Bibliográficos
Autores principales: Lorenzo, Damaris Nadia, Badea, Alexandra, Davis, Jonathan, Hostettler, Janell, He, Jiang, Zhong, Guisheng, Zhuang, Xiaowei, Bennett, Vann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274267/
https://www.ncbi.nlm.nih.gov/pubmed/25533844
http://dx.doi.org/10.1083/jcb.201407063