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The mitochondrial permeability transition pore and its adaptive responses in tumor cells

This review covers recent progress on the nature of the mitochondrial permeability transition pore (PTP) – a key effector in the mitochondrial pathways to cell death – and on the adaptive responses of tumor cells that desensitize the PTP to Ca(2+) and reactive oxygen species (ROS), thereby playing a...

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Detalles Bibliográficos
Autores principales: Rasola, Andrea, Bernardi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274314/
https://www.ncbi.nlm.nih.gov/pubmed/25454774
http://dx.doi.org/10.1016/j.ceca.2014.10.003