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The mitochondrial permeability transition pore and its adaptive responses in tumor cells
This review covers recent progress on the nature of the mitochondrial permeability transition pore (PTP) – a key effector in the mitochondrial pathways to cell death – and on the adaptive responses of tumor cells that desensitize the PTP to Ca(2+) and reactive oxygen species (ROS), thereby playing a...
Autores principales: | Rasola, Andrea, Bernardi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274314/ https://www.ncbi.nlm.nih.gov/pubmed/25454774 http://dx.doi.org/10.1016/j.ceca.2014.10.003 |
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