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Stimulation of Mucin, Mucus, and Viscosity during Lubiprostone in Patients with Chronic Constipation may Potentially Lead to Increase of Lubrication

OBJECTIVES: The purpose of this clinical trial was to explore whether lubiprostone increases the rate of mucus and mucin secretion and its viscosity in chronic constipation (CC) patients. The secretion of chloride (CS) into the gastrointestinal tract lumen is pivotal in the body's ability to pr...

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Detalles Bibliográficos
Autores principales: Majewski, Marek, Sarosiek, Irene, Wallner, Grzegorz, Edlavitch, Stanley A, Sarosiek, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274370/
https://www.ncbi.nlm.nih.gov/pubmed/25521039
http://dx.doi.org/10.1038/ctg.2014.19