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Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase D (PLD) isozymes are dysregulated in various cancers. Recently, we reported th...

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Detalles Bibliográficos
Autores principales: Hwang, Won Chan, Kim, Mi Kyoung, Song, Ju Hyun, Choi, Kang-Yell, Min, Do Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274395/
https://www.ncbi.nlm.nih.gov/pubmed/25475140
http://dx.doi.org/10.1038/emm.2014.74