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Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD
As a member of 18 glycosyl hydrolase (GH) family, chitotriosidase (Chitinase 1, CHIT1) is a true chitinase mainly expressed in the differentiated and polarized macrophages. CHIT1 is an innate immune mediator that digests the cell walls of chitin-containing eukaryotic pathogens, such as fungi. Howeve...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274464/ https://www.ncbi.nlm.nih.gov/pubmed/25553258 http://dx.doi.org/10.4168/aair.2015.7.1.14 |