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Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD

As a member of 18 glycosyl hydrolase (GH) family, chitotriosidase (Chitinase 1, CHIT1) is a true chitinase mainly expressed in the differentiated and polarized macrophages. CHIT1 is an innate immune mediator that digests the cell walls of chitin-containing eukaryotic pathogens, such as fungi. Howeve...

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Detalles Bibliográficos
Autores principales: Cho, Soo Jung, Weiden, Michael D., Lee, Chun Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274464/
https://www.ncbi.nlm.nih.gov/pubmed/25553258
http://dx.doi.org/10.4168/aair.2015.7.1.14