Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice

TRPM7 is an unusual bi-functional protein containing an ion channel covalently linked to a protein kinase domain. TRPM7 is implicated in regulating cellular and systemic magnesium homeostasis. While the biophysical properties of TRPM7 ion channel and its function are relatively well characterized, t...

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Detalles Bibliográficos
Autores principales: Ryazanova, Lillia V., Hu, Zhixian, Suzuki, Sayuri, Chubanov, Vladimir, Fleig, Andrea, Ryazanov, Alexey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274504/
https://www.ncbi.nlm.nih.gov/pubmed/25534891
http://dx.doi.org/10.1038/srep07599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274504/
https://www.ncbi.nlm.nih.gov/pubmed/25534891
http://dx.doi.org/10.1038/srep07599

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