Elucidating the role of the TRPM7 alpha-kinase: TRPM7 kinase inactivation leads to magnesium deprivation resistance phenotype in mice

TRPM7 is an unusual bi-functional protein containing an ion channel covalently linked to a protein kinase domain. TRPM7 is implicated in regulating cellular and systemic magnesium homeostasis. While the biophysical properties of TRPM7 ion channel and its function are relatively well characterized, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Ryazanova, Lillia V., Hu, Zhixian, Suzuki, Sayuri, Chubanov, Vladimir, Fleig, Andrea, Ryazanov, Alexey G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274504/
https://www.ncbi.nlm.nih.gov/pubmed/25534891
http://dx.doi.org/10.1038/srep07599

Ejemplares similares

Ejemplares similares