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Conservation of an intricate circuit for crucial modifications of the tRNA(Phe) anticodon loop in eukaryotes

Post-transcriptional tRNA modifications are critical for efficient and accurate translation, and have multiple different roles. Lack of modifications often leads to different biological consequences in different organisms, and in humans is frequently associated with neurological disorders. We invest...

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Detalles Bibliográficos
Autores principales: Guy, Michael P., Phizicky, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274638/
https://www.ncbi.nlm.nih.gov/pubmed/25404562
http://dx.doi.org/10.1261/rna.047639.114