Analysis of mRNA recognition by human thymidylate synthase

Expression of hTS (human thymidylate synthase), a key enzyme in thymidine biosynthesis, is regulated on the translational level through a feedback mechanism that is rarely found in eukaryotes. At low substrate concentrations, the ligand-free enzyme binds to its own mRNA and stabilizes a hairpin stru...

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Detalles Bibliográficos
Autores principales: Brunn, Nicholas D., Dibrov, Sergey M., Kao, Melody B., Ghassemian, Majid, Hermann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2014
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274661/
https://www.ncbi.nlm.nih.gov/pubmed/25423174
http://dx.doi.org/10.1042/BSR20140137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274661/
https://www.ncbi.nlm.nih.gov/pubmed/25423174
http://dx.doi.org/10.1042/BSR20140137

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