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Plasminogen activation by staphylokinase enhances local spreading of S. aureus in skin infections

BACKGROUND: Staphylococcus aureus (S. aureus) is a frequent cause of skin and soft tissue infections. A unique feature of S. aureus is the combined presence of coagulases that trigger fibrin formation and of the plasminogen activator staphylokinase (SAK). Whereas the importance of fibrin generation...

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Detalles Bibliográficos
Autores principales: Peetermans, Marijke, Vanassche, Thomas, Liesenborghs, Laurens, Claes, Jorien, Vande Velde, Greetje, Kwiecinksi, Jakub, Jin, Tao, De Geest, Bart, Hoylaerts, Marc F, Lijnen, Roger H, Verhamme, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4274676/
https://www.ncbi.nlm.nih.gov/pubmed/25515118
http://dx.doi.org/10.1186/s12866-014-0310-7